Stereoselective total synthesis and structural revision of the diacetylenic diol natural products strongylodiols H and I

• Pamarthi Gangadhar,
• Sayini Ramakrishna,
• Ponneri Venkateswarlu and
• Pabbaraja Srihari

Beilstein J. Org. Chem. 2018, 14, 2313–2320, doi:10.3762/bjoc.14.206

• reaction steps. A common aldehyde intermediate has been used for the synthesis of both strongylodiols. Keywords: alkylation; Cadiot–Chodkiewicz coupling; Corey–Bakshi–Shibata reduction; Mosher’s analysis; Wittig reaction; Introduction Diacetylenic polyol compounds [1][2] originated from marine sources